Infran Khan's role in The Amazing Spider-Man continues to be one of the more mysterious ones since his casting as he was referred to as Van Atter, which sort of connects to the Nels Van Adder character from the comics world and would certainly make sense in a reboot of the franchise. Still, there hasn't been a clean indication of what the role will be and speculation has largely fallen off the map since his initial casting. Khan is now quoted in talking with NDTV which MTV Splash Page picked up about his role and how he feels it's going to be in the feature.
"The role [in HBO's 'In Treatment'] got me some good reviews there and I think the industry there is aware of my work," said Irrfan Khan "Marc [Webb] had seen me and wanted to work with me and approached me for this role. I play one of the villains in the movie. It is a pivotal role."
With him stating it will be pivotal, that certainly seems to indicate more of what we saw with the comics Van Adder character through some retconning over the years to talk about the early experiments by Norman Osborn.